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Contact: {kerenl,oranit}@post.tau.ac.ill |
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EMatch is a novel
knowledge-based computational method towards tackling this task for
cryo-EM maps at 6-10 A resolution. The method recognizes and
locates possible atomic resolution structural homologues of protein
domains in the assembly.
References:
- Lasker K, Dror O, Nussinov R, Wolfson H.J. Discovery of Protein
Substructures in EM Maps. Algorithms in Bioinformatics: 5th
International Workshop, WABI 2005, Mallorca, Spain, October 3-6, 2005,
Proceedings, edited by R. Casadio & G. Myers, vol. 3692 of Lecture
Notes in Computer Science, pp. 423-434. Springer
- Dror O, Lasker K, Nussinov R, Wolfson H.J. EMatch: An Efficient
Method for Aligning Atomic Resolution Subunits into Intermediate
Resolution Cryo-EM Maps of Large Macromolecular Assemblies, Acta
crystallography D, submitted.
- Lasker K, Dror O, Shatsky M, Nussinov R, Wolfson H.J. EMatch:
Discovery of High Resolution Structural Homologues of Protein Domains
In Intermediate Resolution Cryo- EM Maps, IEEE/ACM Transactions
on Computational Biology and Bioinformatics, in press.