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Multiple Alignment of Protein-Protein InterfaceS (PPIs)
Recognizes spatially conserved chemical interactions shared by a set of PPIs

Type PDB and chain IDs (e.g 1cse E:I, 4sgb E:I, 1cbw HG:I):             
or upload a ZIP file with complexes' structures:             
Email address (optional):             
              

* The link to the output page will be sent by email *


Please cite the following references:
1. Shulman-Peleg A, Shatsky M, Nussinov R. and Wolfson H.J. Spatial chemical conservation of hot spot interactions in protein-protein complexes. BMC Biol. 2007 Oct 9;5(1):43 [Link].
2. Shulman-Peleg A, Shatsky M, Nussinov R. and Wolfson H.J. MultiBind and MAPPIS: Web servers for multiple alignment of protein 3D binding sites and their interactions, Nucleic Acids Research, 2008, Vol. 36, W260-W264. [Link].
Alexandra Shulman-Peleg

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