SymmRef is a method for refinement and re-ranking of symmetric docking solutions, with Cn symmetry. The method models backbone and side-chain movements and optimizes the rigid-body orientations of the monomers. The backbone movements are modeled by normal modes minimization and the conformations of the side-chains are modeled by selecting optimal rotamers.
Here you can download an executable version of SymmRef1.2 for Linux operating system.
This application is free for accademic use.
If you use SymmRef, please cite:
Efrat Mashiach-Farkash, Ruth Nussinov and Haim J. Wolfson. SymmRef: A flexible refinement method for symmetric multimers . PROTEINS, 2011.